Olanzapine/samidorphan will reduce the level or result of hydromorphone by pharmacodynamic antagonism. Contraindicated. Samidorphan elicits opioid antagonistic consequences and will increase risk of precipitating acute opioid withdrawal in clients dependent on opioids. diazepam intranasal and hydromorphone both of those increase sedation. Keep away from or Use Alternate Drug. Limit use https://richardo951mxb0.blogripley.com/profile