At three times article-MPTP, we observed considerable microglial activation and up-regulation of CB2 cannabinoid receptors from the ventral midbrain. Remedy with Get or the CB2 receptor agonist JWH015 (4 mg/kg, intraperitoneal) lessened MPTP-induced microglial activation, Whilst genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. Also, Persistent Earn reversed MPTP-l... https://win55.clinic/tin-tuc