Pentobarbital will reduce the extent or result of saxagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known. pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers can minimize panobinostat stages by ~70% and cause treatment method failure. pentobarbit... https://stevenw741efh9.vigilwiki.com/user