Increasing resistance to every major class of antibiotics and a dearth of novel classes of antibacterial agents in development pipelines has created a dwindling reservoir of treatment options for serious bacterial infections. The bacterial type IIA topoisomerases. DNA gyrase and topoisomerase IV. are validated antibacterial drug targets with multiple prospective drug binding sites. https://www.roneverhart.com/Echo-Fix-EF-P2-Spring-Reverb-Pedal-p32083/